Tyrosine-Protein Kinase Syk
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
LEU-369
LEU-370
3.6
3.9
-1.2
-5.5
38.6
43.5
159.4
LEU-370
THR-371
0.6
0.6
0.7
-2.1
86.9
87.1
-62.2
THR-371
LEU-372
4.0
3.8
2.0
3.7
131.9
129.2
-83.2
LEU-372
GLU-373
6.0
6.0
-10.7
-10.3
70.5
69.0
-25.9
GLU-373
ASP-374
8.9
8.5
23.2
-12.2
73.7
89.2
38.0
ASP-374
LYS-375
12.4
12.1
30.7
-9.0
135.1
143.9
-350.3
LYS-375
GLU-376
13.3
11.2
-39.9
20.2
85.9
98.4
-113.9
GLU-376
LEU-377
12.8
12.5
-31.0
5.2
14.4
23.0
495.4
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
VAL-399
ALA-400
2.2
2.5
2.5
3.6
83.5
87.4
45.5
ALA-400
VAL-401
5.4
5.8
1.0
3.5
145.1
146.2
-32.9
VAL-401
LYS-402
7.3
7.5
1.7
2.4
93.2
93.5
-58.2
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees