Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-207   ASP-208  1.9 1.5 22.6 -22.4 109.1 112.3 -0.4
 ASP-208   THR-209  2.0 2.3 34.2 -10.4 75.6 74.5 28.8
 THR-209   LEU-210  4.2 4.7 -1.5 -9.2 35.0 31.3 12.1
 LEU-210   GLN-211  5.1 5.4 -13.0 -8.3 53.4 60.8 45.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-341   LEU-342  4.7 5.0 -27.3 -8.6 95.2 86.8 -20.2
 LEU-342   GLN-343  2.1 2.5 -6.1 12.4 161.5 153.2 27.1
 GLN-343   SER-344  2.0 2.2 -22.1 0.2 83.8 91.4 17.5
 SER-344   PRO-345  5.7 5.9 23.9 1.0 20.3 23.4 72.6
 PRO-345   GLU-346  6.7 6.9 -5.6 -3.1 91.7 90.3 10.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-474   ALA-475  8.7 8.3 2.3 -23.9 159.6 149.0 76.5
 ALA-475   PRO-476  8.7 8.9 -5.9 -5.2 66.0 58.8 -24.6
 PRO-476   GLY-477  8.4 8.2 -5.4 -57.2 67.3 48.1 102.3
 GLY-477   ARG-478  5.2 5.3 53.9 -28.2 161.9 110.3 -66.3
 ARG-478   TYR-479  4.2 3.6 56.8 -2.2 100.6 106.6 -16.2
 TYR-479   ASP-480  2.5 2.3 11.0 -32.8 152.5 154.8 41.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees