Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-82   ASP-83  16.8 16.8 -0.3 -0.9 126.8 123.1 -28.5
 ASP-83   THR-84  14.1 14.2 -12.7 5.2 64.1 66.4 19.7
 THR-84   LYS-85  10.7 10.9 -14.5 1.5 119.0 122.3 -26.5
 LYS-85   GLY-86  7.8 8.7 9.5 7.6 66.8 74.1 25.6
 GLY-86   PRO-87  5.4 5.6 -12.1 6.2 97.3 87.8 -5.8
 PRO-87   GLU-88  1.9 2.0 68.3 -11.1 36.8 36.4 135.9
 GLU-88   ILE-89  2.8 3.5 -16.7 11.9 81.9 88.7 -13.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-178   LEU-179  3.7 3.9 28.4 -15.0 107.9 106.4 -4.3
 LEU-179   PRO-180  5.1 5.6 -2.1 -15.5 68.5 55.0 -19.0
 PRO-180   GLY-181  4.3 5.1 -150.8 -164.3 92.8 85.2 23.5
 GLY-181   CYS-182  7.6 8.9 -29.0 -7.8 125.7 155.7 -56.7
 CYS-182   ASP-183  8.7 9.1 158.7 -149.4 29.4 52.5 27.3
 ASP-183   VAL-184  9.0 9.6 28.3 -1.0 41.8 35.4 61.7
 VAL-184   ASP-185  6.7 6.9 2.3 -39.7 26.8 33.7 -91.8
 ASP-185   LEU-186  7.5 7.9 -30.5 56.8 122.7 143.3 67.8
 LEU-186   PRO-187  4.0 4.8 14.5 8.1 65.5 63.9 -8.8
 PRO-187   ALA-188  4.6 5.4 0.1 -8.7 109.9 114.7 -0.3
 ALA-188   VAL-189  6.8 6.8 24.3 3.4 70.7 71.8 73.0
 VAL-189   SER-190  5.9 5.6 5.5 10.1 50.3 65.2 16.2
 SER-190   ALA-191  2.6 2.8 -4.7 -1.7 143.7 157.2 -15.6
 ALA-191   LYS-192  2.9 3.2 0.5 2.8 102.8 92.6 11.7
 LYS-192   ASP-193  5.8 6.7 1.2 4.1 107.5 103.0 -8.6
 ASP-193   ARG-194  6.9 7.6 -4.0 11.6 140.3 145.9 18.7
 ARG-194   VAL-195  7.6 7.5 -7.2 -4.3 121.0 121.7 -8.6
 VAL-195   ASP-196  9.0 9.3 17.9 -13.8 124.1 129.5 -17.1
 ASP-196   LEU-197  11.2 11.3 3.2 0.5 87.1 87.4 3.3
 LEU-197   GLN-198  12.5 12.4 2.1 -3.5 31.8 33.5 -0.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees