Akap9-Braf Fusion Protein

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-483   MET-484  9.0 8.5 13.4 -50.4 135.4 130.9 66.7
 MET-484   LEU-485  7.5 6.8 12.2 -19.9 103.5 137.1 -10.0
 LEU-485   ASN-486  6.0 5.1 -43.2 -13.7 8.0 31.8 189.2
 ASN-486   VAL-487  7.4 5.6 -3.8 29.2 65.3 42.9 -45.0
 VAL-487   THR-488  4.1 3.2 23.1 9.4 119.2 106.5 -68.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-502   GLY-503  3.3 3.3 1.1 -11.3 154.0 149.1 27.1
 GLY-503   VAL-504  5.4 5.7 -8.2 3.2 50.7 43.9 16.5
 VAL-504   LEU-505  6.6 6.8 7.9 -2.8 110.0 113.8 9.0
 LEU-505   ARG-506  4.5 4.4 -18.6 -2.3 48.7 46.6 52.3
 ARG-506   LYS-507  1.9 1.6 7.5 11.4 168.6 155.1 -60.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-518   TYR-519  5.3 5.1 -3.9 4.3 33.5 26.3 -10.2
 TYR-519   SER-520  3.7 3.7 30.6 -44.7 136.4 131.1 50.7
 SER-520   THR-521  4.9 5.0 4.0 -15.3 129.7 137.8 24.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-524   LEU-525  3.9 3.7 4.9 -21.8 161.0 152.8 60.6
 LEU-525   ALA-526  1.8 1.5 -5.3 20.6 64.1 59.4 -58.1
 ALA-526   ILE-527  4.3 4.0 -11.5 -16.0 9.0 18.0 95.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees