Pyruvate Kinase Isozymes M1/m2
(All numbering and residues are taken from first PDB file)
Bending Residue Dihedral Analysis
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
THR-113
LYS-114
8.1
8.0
2.3
-4.5
122.5
118.8
-4.8
LYS-114
GLY-115
7.4
7.3
-1.8
-16.8
75.4
76.3
8.7
GLY-115
PRO-116
3.6
3.6
23.8
-0.2
78.8
95.1
6.8
PRO-116
GLU-117
3.7
3.8
-80.5
64.3
32.1
43.8
53.9
GLU-117
ILE-118
6.7
6.7
-10.2
-5.6
99.5
101.7
32.3
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees
Residue
iResidue
i+1Distance of hinge axis to residue i in
(A) Distance of hinge axis to residue i in
(A) Change in
(deg) Change in
(deg) Angle of psi(i) axis to hinge axis
(deg) Angle of psi(i) axis to hinge axis
(deg) Percentage Progress
PRO-218
ALA-219
4.9
4.5
-8.7
-1.3
122.4
117.6
-13.3
ALA-219
VAL-220
4.0
3.1
-11.7
7.9
79.8
67.0
-8.6
VAL-220
SER-221
1.3
1.2
-34.2
7.4
61.8
54.1
69.4
SER-221
GLU-222
2.4
2.4
7.7
-7.0
150.2
144.6
-13.1
GLU-222
LYS-223
3.8
4.2
-7.5
5.1
97.3
104.8
17.9
LYS-223
ASP-224
6.6
6.9
-4.2
0.9
105.8
104.9
-2.5
ASP-224
ILE-225
5.3
5.3
3.5
-13.7
140.6
141.6
46.9
Graph shows rotational transition at bending residues and can be used
to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees