Topoisomerase V

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  TYR-289   LEU-290  6.8 6.4 -13.4 -3.4 36.9 33.4 124.9  LEU-290   GLU-291  9.0 8.1 9.9 8.2 119.0 120.2 -52.5  GLU-291   GLN-292  7.0 5.8 -19.9 0.8 52.8 38.2 111.6 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees