G Protein-Coupled Receptor Kinase 6

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-226   GLY-227  16.1 15.0 10.5 -4.4 123.4 122.9 -37.4
 GLY-227   GLU-228  13.8 12.7 -1.7 -2.0 92.0 89.3 55.3
 GLU-228   ALA-229  11.0 9.9 -15.7 4.3 77.8 83.2 14.2
 ALA-229   MET-230  8.8 7.5 9.5 -17.5 170.1 155.8 89.5
 MET-230   ALA-231  9.9 8.7 5.2 -0.7 122.1 135.0 -61.5
 ALA-231   LEU-232  8.8 8.0 17.2 -5.1 81.7 86.1 -30.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-235   GLN-236  3.3 2.6 28.4 -25.8 101.5 100.4 7.0
 GLN-236   ILE-237  0.2 0.7 2.3 5.7 51.8 56.8 15.0
 ILE-237   LEU-238  2.7 3.3 8.8 3.6 28.3 27.0 86.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-241   ASN-242  5.5 6.4 14.9 -17.2 143.2 139.9 28.5
 ASN-242   SER-243  6.9 7.5 42.3 -46.7 138.7 142.1 -43.5
 SER-243   ARG-244  7.3 7.7 -11.4 3.7 28.6 29.7 112.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-247   SER-248  2.0 2.1 -0.8 2.0 45.6 48.6 -25.8
 SER-248   LEU-249  1.5 1.6 -12.4 14.6 69.1 65.5 122.2
 LEU-249   ALA-250  3.8 3.4 -12.5 15.9 89.9 96.0 13.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-263   THR-264  5.8 5.1 -3.4 -1.4 11.5 11.9 17.3
 THR-264   LEU-265  4.1 3.4 -10.5 22.0 60.8 62.4 0.1
 LEU-265   MET-266  6.4 5.6 -2.3 -6.6 41.3 52.7 42.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-465   LYS-466  9.3 9.6 24.9 -23.8 110.4 106.0 -10.5
 LYS-466   PRO-467  5.9 6.5 0.7 -14.3 89.4 93.4 -53.2
 PRO-467   ASP-468  7.3 8.3 13.7 13.9 49.1 61.0 99.1
 ASP-468   PRO-469  8.5 9.8 17.1 -1.9 126.8 120.8 -112.7
 PRO-469   GLN-470  8.1 9.2 123.0 -16.8 91.9 110.8 -171.9
 GLN-470   ALA-471  11.7 12.1 120.0 41.4 116.3 117.0 1293.5
 ALA-471   ILE-472  12.9 14.1 22.4 -43.3 171.4 157.1 164.1
 ILE-472   TYR-473  14.2 14.9 30.6 -97.2 107.3 83.5 -130.0
 TYR-473   CYS-474  14.1 18.3 125.4 1.9 152.7 136.3 -746.9
 GLU-492   PRO-493  19.7 17.4 170.6 -18.9 93.9 99.5 -85.8
 PRO-493   THR-494  17.5 15.1 -2.0 12.3 98.9 109.1 82.3
 THR-494   ASP-495  14.3 12.2 -31.1 14.0 164.0 167.5 -105.2
 ASP-495   GLN-496  14.6 13.5 -12.2 -6.7 112.0 111.0 -30.0
 GLN-496   ASP-497  15.1 14.3 13.5 -11.2 95.7 97.6 9.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-501   PHE-502  7.9 7.5 5.9 -3.7 168.2 163.4 -11.9
 PHE-502   ALA-503  8.1 7.5 0.3 -5.8 130.3 133.6 27.1
 ALA-503   THR-504  11.0 10.5 1.1 -21.7 88.2 88.9 21.0
 THR-504   GLY-505  10.0 10.2 33.4 -9.2 129.0 144.4 -39.5
 GLY-505   SER-506  12.0 11.9 16.2 3.1 133.5 135.6 -69.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees