Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-84   LYS-85  7.8 7.4 9.7 -17.9 132.3 131.3 27.3
 LYS-85   GLY-86  7.3 6.5 -23.7 0.4 72.3 68.4 12.9
 GLY-86   PRO-87  3.5 2.8 35.4 -8.7 95.4 118.2 -55.8
 PRO-87   GLU-88  3.4 3.0 -104.4 44.2 27.0 36.0 217.3
 GLU-88   ILE-89  6.1 5.3 -3.8 -4.3 81.5 92.8 -55.8
 ILE-89   ARG-90  8.5 8.5 16.9 4.4 115.3 112.6 -37.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-187   ALA-188  5.5 5.5 -15.6 6.0 105.8 108.9 -14.6
 ALA-188   VAL-189  3.8 3.8 -33.7 25.1 72.7 66.4 57.8
 VAL-189   SER-190  0.7 1.3 -21.5 -2.4 74.5 66.0 42.4
 SER-190   ALA-191  3.2 3.0 -5.7 6.8 17.2 29.8 -24.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees