Serine/threonine-Protein Kinase Pak 4

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-352   ASP-353  11.0 10.9 6.6 4.8 27.1 28.2 53.1
 ASP-353   LEU-354  13.2 13.3 -2.5 -10.7 138.8 135.9 -47.3
 LEU-354   ARG-355  11.2 11.2 5.1 15.3 54.5 49.9 60.6
 ARG-355   LYS-356  14.6 14.4 -0.7 13.4 65.1 68.9 5.4
 LYS-356   GLN-357  16.3 15.5 -38.5 28.9 67.7 85.5 34.6
 GLN-357   GLN-358  14.7 12.7 -28.3 -23.0 123.4 134.1 -153.8
 GLN-358   ARG-359  16.9 14.6 23.7 13.9 60.4 84.3 26.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-360   GLU-361  10.8 9.2 -8.4 -13.9 85.7 85.6 2.9
 GLU-361   LEU-362  8.8 8.5 -10.4 -2.1 23.2 26.0 72.1
 LEU-362   LEU-363  9.4 9.6 -11.0 -5.1 61.1 58.9 30.4
 LEU-363   PHE-364  6.7 6.8 -6.2 4.6 98.0 107.9 10.3
 PHE-364   ASN-365  4.3 4.2 1.0 -0.9 128.2 113.0 5.6
 ASN-365   GLU-366  6.8 6.7 -1.8 -5.9 19.0 13.0 35.9
 GLU-366   VAL-367  5.5 6.0 15.6 -2.2 99.7 100.4 -7.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-377   VAL-378  10.0 10.1 0.1 0.6 143.7 142.0 8.2
 VAL-378   VAL-379  7.9 8.1 -2.0 -6.9 95.2 94.3 31.3
 VAL-379   GLU-380  4.2 4.4 -5.2 -3.5 51.1 43.1 60.0
 GLU-380   MET-381  3.4 3.8 0.6 4.8 121.5 121.2 -7.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-396   PHE-397  2.5 2.3 -3.3 -2.3 67.4 64.2 -24.0
 PHE-397   LEU-398  4.0 3.5 -16.7 1.3 41.1 39.4 55.5
 LEU-398   GLU-399  3.3 2.8 11.8 -36.7 129.3 118.0 81.6
 GLU-399   GLY-400  5.2 5.3 29.6 -14.8 111.7 123.2 -34.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees