Metabotropic Glutamate Receptor 3

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-168   ASP-169  3.4 3.0 6.3 -8.9 106.6 101.4 -2.6
 ASP-169   PHE-170  3.0 1.5 21.4 4.4 70.1 72.0 17.7
 PHE-170   TYR-171  2.1 2.7 -19.5 -3.3 45.6 32.4 52.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-299   LEU-300  6.2 6.2 -11.9 -8.4 90.5 84.1 -7.9
 LEU-300   ALA-301  4.1 4.2 -1.3 16.9 160.7 156.8 64.1
 ALA-301   SER-302  2.8 3.1 -6.8 -5.2 94.8 95.1 -11.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-435   ASP-436  12.2 12.7 -6.4 -2.0 51.1 49.0 30.2
 ASP-436   GLY-437  9.0 9.6 7.5 -36.4 161.3 154.6 95.1
 GLY-437   MET-438  8.8 9.7 -9.4 0.2 76.7 64.6 31.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees