7 Alpha-Hydroxysteroid Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-187   ALA-188  11.8 11.8 5.4 0.3 122.8 121.0 -9.0
 ALA-188   PRO-189  11.1 10.7 -3.8 22.5 55.8 61.5 -28.5
 PRO-189   GLY-190  7.6 7.1 -4.8 -3.8 34.7 23.4 16.8
 GLY-190   ALA-191  6.5 6.0 0.8 -7.0 77.4 84.0 -3.9
 ALA-191   ILE-192  3.3 2.9 -27.3 33.7 120.8 121.8 25.1
 ILE-192   LEU-193  0.8 0.6 -2.8 -15.3 96.6 89.0 5.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-210   GLN-211  1.3 1.2 32.8 1.6 34.0 26.1 87.7
 GLN-211   HIS-212  2.2 2.1 5.0 -22.1 101.6 91.7 8.3
 HIS-212   THR-213  5.5 5.7 8.0 9.0 139.3 137.5 -34.1
 THR-213   PRO-214  6.0 6.3 6.9 -8.2 69.8 65.7 5.0
 PRO-214   ILE-215  9.2 9.5 5.5 1.5 114.1 113.3 -8.9
 ILE-215   ARG-216  9.6 9.7 -3.7 2.8 87.2 90.2 -6.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees