Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-85   GLY-86  10.2 9.8 -16.7 9.2 77.1 75.7 8.1
 GLY-86   PRO-87  6.6 6.5 15.1 -10.6 100.0 103.5 -6.9
 PRO-87   GLU-88  3.9 3.1 -78.5 26.2 24.3 17.8 136.1
 GLU-88   ILE-89  5.7 5.2 23.9 -12.5 92.6 100.6 11.1
 ILE-89   ARG-90  6.9 7.1 3.8 13.9 120.6 117.0 -43.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-186   PRO-187  2.9 3.1 -16.8 1.9 44.7 44.6 15.6
 PRO-187   ALA-188  1.9 1.7 -7.3 4.5 98.3 96.8 -0.1
 ALA-188   VAL-189  3.8 2.7 24.9 -27.5 98.1 106.7 22.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees