Epidermal Growth Factor Receptor

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-296   ASN-297  11.4 11.4 -10.0 2.0 29.5 27.2 98.5
 ASN-297   GLY-298  11.6 11.8 14.9 -1.3 123.5 129.0 -211.4
 GLY-298   PRO-299  14.3 14.1 -13.9 3.0 130.2 134.6 -109.5
 PRO-299   CYS-300  15.5 15.6 16.8 -6.8 49.8 51.2 123.2
 CYS-300   PRO-301  14.0 14.1 14.0 -16.7 97.2 101.3 -38.8
 PRO-301   LYS-302  12.9 12.9 19.7 -16.9 48.0 49.9 81.2
 LYS-302   THR-303  16.0 15.7 40.6 -37.8 36.4 41.0 32.4
 THR-303   CYS-304  15.3 15.8 34.4 -20.0 59.8 61.3 56.9
 CYS-304   PRO-305  18.2 18.4 -1.4 -2.5 147.4 152.0 -84.3
 PRO-305   GLY-306  18.3 18.4 2.0 5.4 88.6 85.0 8.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees