Map Kinase-Activated Protein Kinase 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-58   ILE-59  3.5 3.0 -10.5 8.9 142.7 142.9 2.5
 ILE-59   ILE-60  3.7 3.3 7.7 -1.5 92.2 89.3 -37.0
 ILE-60   ASP-61  7.3 7.0 -24.0 9.3 62.8 71.9 60.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-87   GLU-88  14.2 14.1 20.5 -23.0 153.8 157.3 39.7
 GLU-88   LYS-89  12.0 11.8 -7.0 17.8 86.5 88.7 -17.3
 LYS-89   PHE-90  9.7 9.6 9.6 -12.7 97.7 93.9 -15.9
 PHE-90   ALA-91  6.0 5.8 -6.2 8.5 82.5 87.9 -6.4
 ALA-91   LEU-92  4.5 4.1 -5.5 11.1 139.7 144.3 22.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-118   ARG-119  4.2 4.6 8.7 -20.6 149.6 150.8 95.6
 ARG-119   ILE-120  5.9 6.2 0.3 -0.4 144.2 147.5 -70.4
 ILE-120   VAL-121  5.2 5.4 -6.6 8.2 52.0 53.2 -27.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-122   VAL-123  4.1 5.0 6.8 -0.7 85.2 76.9 110.0
 VAL-123   TYR-124  4.3 4.3 10.5 -6.6 14.6 10.9 20.0
 TYR-124   GLU-125  3.5 3.4 4.7 -2.8 75.2 75.6 14.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees