Thermolysin (E.C.3.4.24.27)

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-75   TYR-76  9.3 9.6 4.1 -8.4 74.1 77.1 -106.8
 TYR-76   ALA-77  6.0 6.2 12.5 -14.6 34.4 39.1 -147.3
 ALA-77   GLY-78  4.9 4.9 8.9 12.9 36.7 34.4 375.9
 GLY-78   VAL-79  7.2 7.6 -9.1 -1.1 92.9 99.3 -76.8
 VAL-79   THR-80  7.6 7.5 -0.4 -2.7 114.4 115.3 -28.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-92   TYR-93  2.4 2.3 10.5 6.4 87.4 85.1 -101.3
 TYR-93   ASP-94  3.7 4.0 -7.7 -1.9 43.8 43.0 242.8
 ASP-94   GLY-95  5.9 6.1 -0.8 2.7 35.3 31.8 -98.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-112   ALA-113  7.8 7.7 17.0 -0.8 40.3 41.7 238.6
 ALA-113   PHE-114  6.8 6.9 4.1 11.2 41.6 48.8 144.1
 PHE-114   TRP-115  8.3 9.0 0.2 -16.6 35.6 29.2 -362.1
 TRP-115   ASN-116  9.0 9.5 -6.4 7.4 93.5 92.7 247.4
 ASN-116   GLY-117  12.6 13.2 -7.1 -1.6 154.2 154.7 -183.9
 GLY-117   SER-118  12.8 13.5 20.8 -18.9 57.3 58.7 81.4
 SER-118   GLU-119  12.6 12.8 3.2 -2.9 112.8 109.0 -45.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-122   GLY-123  7.8 7.4 8.1 -8.9 21.9 27.7 87.0
 GLY-123   ASP-124  8.4 8.2 -10.4 15.7 113.8 114.6 -7.2
 ASP-124   GLY-125  7.3 7.4 -0.7 -10.8 134.3 132.0 -189.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-131   PRO-132  2.8 2.7 13.5 -18.0 16.4 23.8 -93.6
 PRO-132   LEU-133  4.8 4.7 1.4 9.7 48.6 43.2 129.2
 LEU-133   SER-134  2.4 2.4 -8.9 -1.5 144.0 145.1 -90.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-180   ASN-181  11.8 12.1 13.8 -7.0 67.4 51.9 37.0
 ASN-181   LYS-182  14.9 14.8 5.7 40.8 29.3 27.0 1116.6
 LYS-182   ASN-183  14.2 13.0 -52.7 12.5 122.7 137.1 -785.4
 ASN-183   PRO-184  14.0 14.7 22.9 -15.0 110.8 104.6 -464.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees