Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-640   ASP-641  6.4 5.8 -26.0 -5.6 101.6 99.4 -4.2
 ASP-641   PHE-642  3.6 2.4 -27.7 8.7 100.4 121.6 -6.4
 PHE-642   GLY-643  1.2 2.5 -40.8 -41.4 75.5 62.9 46.3
 GLY-643   LEU-644  2.7 3.1 48.5 18.9 53.5 98.2 52.5
 LEU-644   ALA-645  4.3 3.7 146.9 -13.9 81.5 67.7 65.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.2 11.2 -43.5 20.4 50.7 96.3 20.0
 PRO-663   VAL-664  7.0 8.0 -87.4 -20.2 21.2 50.9 113.2
 VAL-664   LYS-665  7.8 8.1 18.0 -9.7 133.8 135.6 -0.3
 LYS-665   TRP-666  6.4 6.3 8.3 1.5 83.3 75.2 -2.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees