Camp-Dependent Protein Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-28   LYS-29  10.9 10.6 -1.0 -7.1 85.5 80.3 -2.1
 LYS-29   TRP-30  7.6 7.1 8.4 -2.3 57.9 58.5 -3.1
 TRP-30   GLU-31  6.6 6.4 0.9 7.4 24.7 25.2 94.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-86   HIS-87  11.4 12.1 18.9 -13.5 28.0 23.4 -39.6
 HIS-87   THR-88  11.9 12.5 15.6 3.2 61.1 62.6 84.7
 THR-88   LEU-89  10.0 10.6 4.4 -2.1 110.8 103.9 42.7
 LEU-89   ASN-90  7.2 7.4 -15.0 19.9 98.5 108.1 27.9
 ASN-90   GLU-91  7.1 8.0 -9.5 8.4 161.8 165.4 -17.4
 GLU-91   LYS-92  6.9 7.7 -8.9 -3.5 99.5 98.4 -9.9
 LYS-92   ARG-93  3.9 4.6 -5.2 -3.4 68.7 72.9 12.4
 ARG-93   ILE-94  2.7 3.3 2.5 -3.2 60.6 53.9 -155.1
 ILE-94   LEU-95  5.5 5.8 15.0 -6.8 34.8 35.3 129.7
 LEU-95   GLN-96  3.4 3.5 6.6 5.7 94.8 94.2 -41.8
 GLN-96   ALA-97  2.1 1.6 -19.4 0.8 72.0 81.9 68.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-104   LYS-105  4.0 3.9 3.3 2.4 41.9 38.6 96.8
 LYS-105   LEU-106  1.4 1.3 -2.3 4.1 114.7 115.4 -15.7
 LEU-106   GLU-107  1.3 1.4 33.8 -28.1 91.0 88.1 -35.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-121   TYR-122  2.4 3.0 9.6 -4.2 52.6 61.3 -9.0
 TYR-122   VAL-123  4.5 5.2 1.0 3.4 47.0 49.0 1.6
 VAL-123   PRO-124  4.3 4.5 11.5 -4.1 48.8 48.7 33.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-315   PRO-316  8.4 8.2 23.1 -26.1 99.5 100.6 -20.4
 PRO-316   LYS-317  8.5 7.5 5.3 70.4 112.9 114.5 -197.4
 ASP-328   ASP-329  23.8 18.2 24.1 -18.7 38.6 67.0 37.9
 ASP-329   TYR-330  21.5 20.2 -70.6 -17.6 157.8 141.4 -644.3
 TYR-330   GLU-331  22.2 21.4 -2.8 -3.5 103.8 93.3 26.6
 GLU-331   GLU-332  25.1 24.1 28.4 -37.3 43.3 38.8 65.5
 GLU-332   GLU-333  23.8 23.3 -51.9 60.4 157.9 141.1 -19.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees