Proto-Oncogene Tyrosine-Protein Kinase Abl1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-395   VAL-396  9.0 10.0 2.7 -10.9 155.8 157.6 6.8
 VAL-396   LYS-397  8.2 9.1 -5.9 -0.4 73.6 74.4 -0.5
 LYS-397   VAL-398  5.3 6.3 6.7 -3.1 167.9 162.5 -1.9
 VAL-398   ALA-399  5.1 5.6 4.9 0.8 96.5 90.8 -2.3
 ALA-399   ASP-400  1.6 1.9 -14.7 -153.8 7.4 22.5 143.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-417   ALA-418  3.0 0.4 -168.3 -27.2 16.4 34.5 -145.3
 ALA-418   LYS-419  2.8 1.6 -15.4 15.4 76.5 57.5 -3.9
 LYS-419   PHE-420  4.2 3.8 22.7 -40.5 120.3 137.3 7.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees