Vitamin D Hydroxylase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-96   ARG-97  11.0 11.6 4.3 -3.0 93.2 91.3 9.9
 ARG-97   LEU-98  10.3 11.1 7.2 -1.2 123.3 124.7 -28.3
 LEU-98   ARG-99  6.8 7.8 -9.3 7.4 11.1 12.9 -9.6
 ARG-99   LYS-100  7.4 8.5 -2.4 3.1 62.8 67.0 18.0
 LYS-100   LEU-101  10.6 11.9 -7.4 -2.6 79.5 75.6 21.3
 LEU-101   VAL-102  9.8 11.2 -15.8 41.6 38.0 39.7 -149.9
 VAL-102   GLY-103  7.2 8.3 -25.1 -8.8 32.7 29.6 197.7
 GLY-103   ARG-104  8.6 9.9 14.1 0.7 137.5 111.2 -86.9
 ARG-104   SER-105  11.0 13.0 -5.6 -32.6 51.3 52.9 145.7
 SER-105   PHE-106  8.9 11.5 -22.8 36.6 50.3 52.1 -68.5
 PHE-106   THR-107  6.4 8.0 55.5 -34.4 121.1 124.1 -150.6
 THR-107   VAL-108  9.3 9.7 5.6 -1.2 155.5 142.1 5.4
 VAL-108   ARG-109  8.7 8.6 13.5 -0.7 127.7 136.1 -38.1
 ARG-109   ARG-110  10.7 10.4 -3.1 -4.8 99.7 89.0 -5.0
 ARG-110   MET-111  9.4 8.9 3.0 12.1 109.9 110.5 -74.0
 MET-111   ASN-112  5.7 5.4 1.2 -25.8 174.8 177.1 151.8
 ASN-112   GLU-113  6.6 6.4 5.2 -8.1 106.9 113.7 21.5
 GLU-113   LEU-114  9.0 8.7 11.9 -0.2 89.7 90.5 2.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-144   ILE-145  13.6 13.8 -9.8 5.1 81.8 85.2 -3.7
 ILE-145   PRO-146  10.0 10.3 10.1 1.3 34.4 36.8 60.8
 PRO-146   VAL-147  8.1 8.4 -1.2 -8.6 135.4 132.5 -46.1
 VAL-147   GLN-148  10.8 10.6 8.2 -6.2 101.9 108.4 6.7
 GLN-148   VAL-149  11.6 11.3 4.7 -4.7 81.6 91.3 7.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-223   GLU-224  9.1 10.7 -16.8 18.6 100.2 93.4 -0.1
 GLU-224   GLU-225  6.1 7.5 -7.6 -1.5 137.1 134.4 -23.8
 GLU-225   LEU-226  3.9 5.6 -1.7 -0.2 149.9 160.5 -12.5
 LEU-226   VAL-227  6.7 7.8 -0.6 -12.7 106.0 110.2 -58.5
 VAL-227   ALA-228  7.5 7.9 9.7 9.9 68.3 87.4 60.0
 ALA-228   MET-229  4.4 4.5 -10.4 3.1 153.1 152.3 -28.6
 MET-229   ALA-230  3.1 3.4 0.9 -1.2 48.0 39.4 0.6
 ALA-230   MET-231  6.4 6.1 -3.6 1.6 100.3 94.3 8.9
 MET-231   LEU-232  7.1 6.5 6.8 -5.8 54.3 68.8 -6.8
 LEU-232   LEU-233  4.6 3.6 -0.6 15.1 168.8 175.1 85.2
 LEU-233   LEU-234  3.9 2.8 9.0 -20.9 64.4 61.8 -51.5
 LEU-234   ILE-235  7.7 6.5 5.3 -1.5 75.5 92.5 9.8
 ILE-235   ALA-236  8.7 7.8 -6.0 -12.2 138.6 123.8 -73.6
 ALA-236   GLY-237  6.4 6.2 6.4 -26.6 28.2 9.7 -113.8
 GLY-237   HIS-238  7.0 5.2 7.1 15.6 72.3 58.6 50.9
 HIS-238   GLU-239  10.6 8.7 -55.4 79.2 99.8 104.8 51.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees