Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-712   THR-713  9.0 8.8 2.3 9.4 92.0 83.8 -20.2
 THR-713   LYS-714  6.1 5.7 6.3 -17.4 144.9 142.6 54.3
 LYS-714   GLY-715  6.7 6.4 -0.7 -15.9 67.4 68.2 33.3
 GLY-715   PRO-716  3.5 3.6 12.5 -2.2 107.3 123.3 -47.9
 PRO-716   GLU-717  5.1 5.2 -92.8 67.9 31.7 32.0 138.8
 GLU-717   ILE-718  7.5 6.9 4.1 -2.2 107.2 107.6 -42.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-816   LEU-817  11.7 11.7 -3.9 3.2 53.6 45.0 69.4
 LEU-817   PRO-818  9.4 9.5 10.2 -10.7 137.5 132.5 16.4
 PRO-818   ALA-819  7.9 7.8 -6.2 -9.3 100.4 99.8 2.3
 ALA-819   VAL-820  5.0 4.6 -1.0 1.0 77.9 54.3 7.4
 VAL-820   SER-821  3.5 3.7 -37.8 -3.7 87.7 74.9 52.4
 SER-821   GLU-822  6.6 6.9 -3.9 13.5 21.0 33.1 -52.0
 GLU-822   LYS-823  8.5 8.8 -12.8 9.1 84.8 93.3 23.6
 LYS-823   ASP-824  8.7 9.0 -1.2 -10.3 79.2 83.1 11.1
 ASP-824   ILE-825  5.2 5.4 10.1 -8.0 164.2 163.4 -12.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees