Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-85   GLY-86  7.3 6.7 -17.8 -5.0 70.3 68.6 21.3
 GLY-86   PRO-87  3.6 3.1 25.4 6.1 95.1 117.8 -53.5
 PRO-87   GLU-88  4.0 3.7 -88.6 32.0 26.2 40.1 199.9
 GLU-88   ILE-89  6.5 6.0 -38.6 12.9 79.2 83.6 -65.8
 ILE-89   ARG-90  8.9 8.8 14.4 -5.2 115.1 115.1 -20.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-187   ALA-188  5.6 5.9 -8.4 10.6 103.4 106.9 -7.6
 ALA-188   VAL-189  3.4 3.9 -15.9 19.0 78.3 71.1 38.7
 VAL-189   SER-190  0.4 1.0 -27.8 14.4 72.3 66.5 16.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees