Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-636   MET-637  17.6 17.0 4.6 -9.2 73.3 72.0 -2.5
 MET-637   LYS-638  14.4 13.7 4.3 -4.5 126.8 127.1 0.6
 LYS-638   ILE-639  11.3 10.5 2.9 0.1 65.0 62.1 -0.1
 ILE-639   ALA-640  8.1 7.4 6.0 -5.9 134.1 132.7 -0.6
 ALA-640   ASP-641  5.2 4.3 0.2 144.8 67.1 52.5 70.0
 ASP-641   PHE-642  1.9 1.2 36.0 -10.6 75.4 115.5 -31.8
 PHE-642   GLY-643  2.2 4.6 -55.5 -17.7 86.7 114.2 -14.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-664   LYS-665  5.3 5.2 22.0 -8.3 122.6 122.9 -3.3
 LYS-665   TRP-666  3.7 3.4 1.9 0.7 74.3 69.4 -6.2
 TRP-666   MET-667  0.8 0.8 2.4 10.1 92.3 92.8 1.5
 MET-667   ALA-668  3.1 3.0 -10.9 12.3 30.5 41.9 -3.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees