DNA Mismatch Repair Protein Muts

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TYR-404   ASP-405  8.4 9.0 -21.5 1.5 60.6 70.8 95.2
 ASP-405   PRO-406  7.7 8.0 4.4 -4.5 119.1 129.4 6.8
 PRO-406   ASP-407  4.5 4.5 1.5 5.6 172.2 163.5 -64.1
 ASP-407   LEU-408  6.3 6.2 -22.2 32.4 62.1 60.2 -80.7
 LEU-408   ASP-409  7.3 8.2 -21.0 20.1 92.6 85.1 -6.5
 ASP-409   ALA-410  5.4 6.4 -15.0 10.7 42.6 41.3 61.5
 ASP-409   ALA-410  5.4 6.4 -15.0 10.7 42.6 41.3 61.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-409   ALA-410  5.4 6.4 -15.0 10.7 42.6 41.3 61.5
 ASP-409   ALA-410  5.4 6.4 -15.0 10.7 42.6 41.3 61.5
 ALA-410   LEU-411  2.7 3.5 -16.1 9.5 30.7 25.7 45.4
 LEU-411   ARG-412  5.4 5.8 0.0 9.0 95.8 98.5 41.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-416   GLU-417  10.1 10.6 5.6 3.2 51.5 56.9 20.1
 GLU-417   GLY-418  9.2 9.4 -2.6 8.4 161.7 161.3 58.0
 GLY-418   VAL-419  8.2 9.1 -19.1 22.8 109.8 101.5 -7.8
 VAL-419   ALA-420  11.8 12.8 5.6 -8.9 96.2 94.0 3.9
 VAL-419   ALA-420  11.8 12.8 5.6 -8.9 96.2 94.0 3.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-419   ALA-420  11.8 12.8 5.6 -8.9 96.2 94.0 3.9
 VAL-419   ALA-420  11.8 12.8 5.6 -8.9 96.2 94.0 3.9
 ALA-420   TYR-421  13.4 13.7 -13.9 -7.8 28.1 25.0 193.6
 TYR-421   PHE-422  11.9 12.2 19.3 -25.9 130.3 131.9 20.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-482   GLU-483  6.9 6.4 -7.3 20.8 47.7 35.7 -74.4
 GLU-483   LYS-484  4.0 3.5 5.3 -4.5 158.9 147.0 -12.0
 LYS-484   GLU-485  5.9 6.0 24.8 -33.8 102.0 96.3 -32.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees