Fibroblast Growth Factor Receptor 3

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 MET-531   ILE-532  9.2 10.2 -27.4 5.1 93.3 98.7 23.7
 ILE-532   GLY-533  5.9 6.8 1.0 10.6 99.3 112.3 13.1
 GLY-533   LYS-534  7.7 8.6 33.2 -16.5 127.3 135.7 -20.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ILE-538   ILE-539  2.8 3.2 29.0 -19.1 34.5 32.6 27.4
 ILE-539   ASN-540  0.6 1.1 -30.3 4.1 80.7 73.5 12.9
 ASN-540   LEU-541  4.0 4.6 36.4 -9.0 73.0 60.6 65.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 VAL-555   GLU-556  5.1 5.4 8.5 -11.6 128.0 129.3 12.1
 GLU-556   TYR-557  2.8 3.0 11.4 -27.7 118.7 116.5 38.0
 TYR-557   ALA-558  0.3 0.4 8.2 -5.3 78.2 87.3 9.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-632   ILE-633  5.1 5.3 6.0 -9.2 115.8 114.7 0.2
 ILE-633   ALA-634  4.6 4.4 -1.9 17.7 110.4 107.1 18.0
 ALA-634   ASP-635  4.6 4.0 -23.2 -0.9 61.0 49.4 69.3
 ASP-635   PHE-636  7.6 6.2 -37.3 0.1 163.8 170.1 -176.6
 ASP-635   PHE-636  7.6 6.2 -37.3 0.1 163.8 170.1 -176.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ASP-635   PHE-636  7.6 6.2 -37.3 0.1 163.8 170.1 -176.6
 ASP-635   PHE-636  7.6 6.2 -37.3 0.1 163.8 170.1 -176.6
 PHE-636   GLY-637  7.4 4.5 -39.4 -48.6 105.3 114.3 -78.7
 GLY-637   LEU-638  11.2 6.7 53.9 25.4 18.7 91.7 230.7
 LEU-638   ALA-639  11.5 9.9 66.8 119.8 49.7 22.9 833.2
 ALA-639   ARG-640  8.1 11.1 -84.8 -13.9 132.1 131.8 -497.8
 ARG-640   ASP-641  8.6 8.2 -47.5 -88.5 116.1 112.4 -296.5
 ASP-641   VAL-642  7.6 6.5 -33.3 -26.9 162.6 169.4 -286.9
 VAL-642   HIS-643  5.9 6.2 86.0 -95.9 54.6 62.7 -36.4
 HIS-643   ASN-644  6.6 3.3 -140.3 -108.6 146.8 127.4 499.9
 ASN-644   LEU-645  7.5 5.9 -78.0 -31.0 102.0 164.3 -461.6
 LEU-645   ASP-646  6.7 5.2 135.6 -3.1 75.8 82.4 73.3
 LEU-645   ASP-646  6.7 5.2 135.6 -3.1 75.8 82.4 73.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-645   ASP-646  6.7 5.2 135.6 -3.1 75.8 82.4 73.3
 LEU-645   ASP-646  6.7 5.2 135.6 -3.1 75.8 82.4 73.3
 ASP-646   TYR-647  5.1 7.0 -178.1 88.3 48.9 32.7 376.7
 TYR-647   TYR-648  7.5 8.1 16.3 -47.0 118.9 108.7 16.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees