Shp-2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  GLN-214   PRO-215  9.9 10.7 -1.3 -18.3 81.8 85.6 4.1  PRO-215   LEU-216  6.4 7.2 -4.5 -3.0 99.5 114.3 -5.3  LEU-216   ASN-217  3.7 4.2 -166.5 139.7 166.3 157.7 -18.0  ASN-217   THR-218  4.1 3.1 16.5 12.4 82.0 71.4 8.4  THR-218   THR-219  2.0 1.7 143.0 8.1 16.8 7.5 113.1  THR-219   ARG-220  2.6 1.8 11.0 -3.3 66.9 74.4 4.3 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees