Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-467   ASP-468  7.4 7.4 -9.9 -9.9 75.3 82.5 -24.1
 ASP-468   PRO-469  5.5 5.2 -8.2 -3.0 116.5 124.7 -71.3
 PRO-469   ARG-470  8.7 8.4 -18.1 16.6 121.8 123.2 -35.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-484   GLY-485  6.4 6.0 6.3 -27.2 80.0 84.3 -32.0
 GLY-485   GLU-486  9.8 9.6 -1.9 34.2 133.7 148.2 242.8
 GLU-486   GLY-487  12.7 12.4 -33.3 26.6 112.0 107.2 68.0
 GLY-487   ALA-488  15.8 14.3 16.4 -11.9 72.1 50.3 58.3
 ALA-488   PHE-489  18.8 16.7 1.8 17.4 64.7 54.1 143.3
 PHE-489   GLY-490  16.9 15.0 -58.7 11.7 102.5 80.0 10.3
 GLY-490   GLN-491  13.1 12.2 34.5 13.5 150.7 161.2 -374.2
 GLN-491   VAL-492  10.5 10.2 6.2 -6.5 85.3 86.8 -23.9
 VAL-492   VAL-493  6.8 6.5 3.2 4.1 142.6 142.9 -52.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-513   LYS-514  3.2 3.2 -4.2 1.2 93.8 94.4 -1.4
 LYS-514   MET-515  5.8 5.6 -10.9 13.7 122.8 122.6 7.6
 MET-515   LEU-516  9.0 8.8 4.1 -2.6 95.2 89.7 -3.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-528   ILE-529  9.8 9.4 -2.4 -2.7 46.1 45.9 33.1
 ILE-529   SER-530  8.0 7.8 5.2 -10.2 103.9 110.5 -35.5
 SER-530   GLU-531  9.1 8.9 16.2 -13.7 48.4 50.1 -25.9
 GLU-531   MET-532  8.6 8.3 2.0 8.8 93.5 92.1 22.0
 MET-532   GLU-533  4.8 4.5 -5.6 3.2 36.7 37.1 13.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-546   LEU-547  8.1 8.0 6.9 2.3 95.6 93.3 10.0
 LEU-547   LEU-548  4.8 4.7 4.4 -10.7 89.3 86.7 -11.3
 LEU-548   GLY-549  5.0 5.3 -3.4 10.6 49.6 55.4 -43.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-561   GLU-562  2.5 2.7 2.1 -2.8 148.9 147.4 32.5
 GLU-562   TYR-563  5.2 5.4 -1.6 -0.9 35.1 34.7 26.8
 TYR-563   ALA-564  4.3 4.4 10.9 -12.3 120.9 119.4 39.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees