Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-640   ASP-641  6.4 5.8 -24.2 -5.8 101.5 99.9 -3.7
 ASP-641   PHE-642  3.5 2.4 -24.3 1.4 100.7 120.4 -6.4
 PHE-642   GLY-643  1.2 2.5 -34.8 -45.0 75.4 60.4 48.3
 GLY-643   LEU-644  2.7 3.2 41.7 28.6 53.3 96.9 53.2
 LEU-644   ALA-645  4.3 3.6 145.7 -18.7 81.1 68.8 58.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  9.2 11.3 -43.2 17.9 50.9 96.1 22.0
 PRO-663   VAL-664  7.0 8.0 -86.2 -19.3 20.9 51.1 111.7
 VAL-664   LYS-665  7.8 8.2 15.4 -6.9 133.9 134.8 -0.3
 LYS-665   TRP-666  6.4 6.3 6.4 4.2 83.7 75.1 -0.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees