Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-519   GLY-520  4.1 4.4 15.2 -0.9 51.3 53.5 32.8  GLY-520   ILE-521  1.9 2.1 -9.0 -2.5 53.7 51.8 49.1  ILE-521   SER-522  4.6 4.6 1.6 -0.3 116.6 113.6 22.8 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-725   GLU-726  7.4 7.6 3.9 -17.6 109.4 112.6 15.0  GLU-726   SER-727  5.1 5.2 4.9 8.0 53.8 51.0 32.1  SER-727   THR-728  1.5 1.6 -3.7 8.9 133.4 133.2 57.3  THR-728   MET-729  4.2 4.5 -7.6 1.1 150.0 150.5 -50.5  MET-729   ASN-730  4.9 5.4 3.0 -1.7 63.6 60.4 -1.6  ASN-730   GLU-731  2.5 2.7 -3.2 -1.9 121.0 123.7 -25.0  GLU-731   TYR-732  1.4 1.5 5.5 -4.3 33.6 36.3 17.8  TYR-732   ILE-733  3.5 4.0 0.0 -0.4 40.3 41.8 9.5  ILE-733   GLU-734  2.7 3.2 1.6 -4.4 67.9 67.8 -33.6  GLU-734   GLN-735  1.5 1.1 3.1 -3.4 45.2 43.4 4.0  GLN-735   ARG-736  2.6 2.3 1.2 -1.0 39.6 38.5 -2.9 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-748   ASP-749  5.1 5.1 -4.6 -8.3 38.5 36.2 61.9  ASP-749   SER-750  2.5 2.4 2.6 1.1 72.6 72.4 34.0  SER-750   LYS-751  1.8 2.0 12.1 -24.0 101.3 106.2 17.5  LYS-751   GLY-752  5.5 5.7 9.0 -0.6 59.5 51.3 13.2 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees