Hexokinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-110   VAL-111  2.3 2.1 -5.8 8.1 49.6 51.9 -8.4
 VAL-111   VAL-112  1.3 1.5 3.3 -2.0 62.3 61.7 11.1
 VAL-112   ILE-113  5.0 5.1 2.1 4.2 111.5 108.4 -32.3
 ILE-113   ALA-114  7.8 8.0 20.4 -12.3 74.5 78.7 83.8
 ALA-114   GLY-115  11.0 11.4 -12.8 5.7 61.6 66.7 58.3
 GLY-115   THR-116  14.1 14.1 -11.8 7.5 129.1 128.4 -24.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-120   GLU-121  4.3 4.3 -3.8 -15.6 63.7 62.6 85.5
 GLU-121   GLY-122  1.8 1.8 -3.5 8.8 110.5 119.8 20.8
 GLY-122   TYR-123  2.5 2.6 4.3 9.0 111.4 113.7 -18.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-128   LEU-129  5.8 5.8 -0.7 -2.6 123.5 125.2 12.2
 LEU-129   ARG-130  2.4 2.3 -10.0 2.2 66.3 64.2 19.3
 ARG-130   VAL-131  1.6 1.7 6.2 4.3 67.3 60.0 45.3
 VAL-131   GLY-132  4.8 4.8 8.1 -5.9 108.5 107.0 16.7
 GLY-132   GLY-133  8.1 8.1 0.4 -3.9 91.7 94.0 14.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-272   GLY-273  10.8 10.8 10.0 -7.2 91.8 80.7 -20.3
 GLY-273   LYS-274  7.1 7.3 -2.5 44.4 113.2 121.3 70.5
 LYS-274   ARG-275  5.9 5.7 -51.5 17.6 73.2 59.3 48.7
 ARG-275   SER-276  4.2 4.3 -19.4 16.2 15.8 12.8 17.4
 SER-276   PRO-277  5.4 5.9 -2.4 4.9 54.2 56.4 -18.8
 LEU-272   GLY-273  3.7 4.2 10.0 -7.2 98.0 90.4 -37.7
 GLY-273   LYS-274  2.7 2.5 -2.5 44.4 136.5 142.1 264.8
 LYS-274   ARG-275  5.7 5.2 -51.5 17.6 77.3 75.4 24.0
 ARG-275   SER-276  8.9 8.4 -19.4 16.2 47.6 44.1 -0.5
 LEU-272   GLY-273  10.8 10.8 10.0 -7.2 91.8 80.7 -20.3
 GLY-273   LYS-274  7.1 7.3 -2.5 44.4 113.2 121.3 70.5
 LYS-274   ARG-275  5.9 5.7 -51.5 17.6 73.2 59.3 48.7
 ARG-275   SER-276  4.2 4.3 -19.4 16.2 15.8 12.8 17.4
 SER-276   PRO-277  5.4 5.9 -2.4 4.9 54.2 56.4 -18.8
 SER-270   ASP-271  6.2 6.3 -5.5 8.9 138.3 140.7 21.2
 ASP-271   LEU-272  3.0 3.1 -7.6 2.5 75.8 79.5 -3.0
 LEU-272   GLY-273  3.7 4.2 10.0 -7.2 98.0 90.4 -37.7
 GLY-273   LYS-274  2.7 2.5 -2.5 44.4 136.5 142.1 264.8
 LYS-274   ARG-275  5.7 5.2 -51.5 17.6 77.3 75.4 24.0
 ARG-275   SER-276  8.9 8.4 -19.4 16.2 47.6 44.1 -0.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees