Hiv-1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 HIS-96   PRO-97  13.7 18.5 41.5 -7.3 106.9 65.2 -5.1
 PRO-97   ALA-98  15.8 20.9 -134.2 5.0 92.2 51.5 97.0
 ALA-98   GLY-99  19.3 23.1 -163.7 144.3 109.2 66.5 7.4
 GLY-99   LEU-100  21.8 20.4 9.0 13.0 17.4 59.4 50.2
 LEU-100   LYS-101  21.9 21.2 165.3 -11.1 90.4 104.6 -122.3
 LYS-101   LYS-102  24.0 24.0 173.2 20.5 106.9 30.6 -127.8
 LYS-102   LYS-103  26.1 26.8 167.6 -67.1 43.9 66.3 146.8
 LYS-103   LYS-104  26.2 26.5 -9.5 17.4 123.1 136.8 13.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-113   ALA-114  4.4 4.3 56.5 4.4 58.0 45.5 85.0
 ALA-114   TYR-115  3.3 3.3 15.1 -12.6 79.5 74.5 20.9
 TYR-115   PHE-116  1.3 1.8 -33.2 10.4 44.6 47.9 44.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-159   PHE-160  2.7 3.0 -13.3 23.8 115.2 119.5 10.8
 PHE-160   GLN-161  0.7 0.5 -27.7 -19.5 49.1 56.2 65.9
 GLN-161   SER-162  2.5 2.7 7.3 -14.8 98.3 106.5 -9.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees