Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-537   ILE-538  5.0 5.4 -11.0 10.1 82.7 79.9 14.0
 ILE-538   GLY-539  1.5 2.0 0.2 -6.8 101.5 104.4 19.6
 GLY-539   LYS-540  3.9 4.6 11.3 -17.4 147.8 148.2 15.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-544   ILE-545  2.9 2.9 24.7 -11.4 55.8 57.1 17.4
 ILE-545   ASN-546  0.7 0.8 -16.1 -1.6 53.7 45.1 70.9
 ASN-546   LEU-547  4.1 4.0 9.0 5.4 77.3 79.0 78.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-562   TYR-563  5.3 5.3 -0.4 -4.2 39.4 39.1 40.3
 TYR-563   ALA-564  4.1 4.2 18.5 -18.4 102.3 101.5 3.8
 ALA-564   SER-565  1.0 1.5 4.7 -6.3 166.3 164.9 -13.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  5.2 5.3 5.3 14.6 91.2 82.8 -3.6
 ALA-640   ASP-641  4.9 5.0 -29.8 -8.9 72.5 54.6 97.9
 ASP-641   PHE-642  8.1 7.4 -22.8 -0.7 15.6 28.2 124.3
 PHE-642   GLY-643  8.2 6.7 -40.9 -28.2 70.7 40.6 173.2
 GLY-643   LEU-644  11.8 7.5 74.3 -18.2 128.9 85.2 -125.2
 PRO-663   VAL-664  19.9 19.8 -98.8 -21.7 70.0 48.1 356.7
 VAL-664   LYS-665  23.0 22.8 15.5 -8.0 74.9 83.0 -34.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees