Sam-Dependent Mthb Methyltransferase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-120   LEU-121  22.7 22.3 14.0 27.6 27.4 15.8 149.5
 LEU-121   PRO-122  21.7 21.3 20.3 14.8 74.1 71.6 62.4
 SER-143   ASN-144  13.5 14.4 21.7 -6.4 84.7 58.9 87.2
 ASN-144   SER-145  14.8 14.4 -6.8 -6.7 79.6 80.4 15.2
 SER-145   GLN-146  11.2 10.8 1.7 1.3 169.1 160.2 -14.9
 GLN-146   HIS-147  11.3 11.4 3.4 0.7 106.7 95.7 6.6
 HIS-147   ALA-148  14.7 14.7 10.2 -18.2 77.9 77.0 12.7
 ALA-148   GLY-149  14.3 13.7 3.6 -10.4 122.9 124.0 18.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-273   VAL-274  3.3 2.9 -0.4 -3.3 92.0 92.2 12.2
 VAL-274   THR-275  3.8 2.9 7.6 -4.4 26.3 24.6 7.6
 THR-275   ALA-276  6.4 5.4 -2.5 20.6 129.6 129.6 32.5
 ALA-276   ASP-277  5.6 4.8 -29.3 25.8 95.3 84.8 -10.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 TRP-287   GLN-288  2.6 2.6 -3.1 14.8 43.1 45.8 1.6
 GLN-288   LEU-289  3.9 4.4 -19.8 5.0 91.6 106.6 -26.4
 LEU-289   GLN-290  7.3 7.2 6.4 20.2 59.6 36.8 73.3
 GLN-290   HIS-291  8.3 7.0 -8.9 -11.8 70.6 74.7 10.8
 HIS-291   THR-292  7.8 8.5 25.3 15.0 137.4 118.8 -74.5
 THR-292   ALA-293  9.4 10.6 -6.2 14.4 99.5 130.7 32.1
 ALA-293   PHE-294  12.1 12.5 0.8 -17.2 63.6 84.3 -19.8
 PHE-294   THR-295  13.2 14.1 32.3 -23.4 115.3 148.3 -33.1
 THR-295   PRO-296  13.0 13.9 -2.9 -3.7 10.9 51.2 35.2
 PRO-296   GLU-297  14.0 15.2 10.5 -28.7 136.4 169.2 64.4
 GLU-297   ALA-298  14.1 14.8 30.2 10.0 93.9 98.1 -45.3
 ALA-298   ARG-299  10.6 11.2 -14.1 -14.2 46.2 45.5 96.1
 ARG-299   SER-300  7.7 8.7 16.5 -3.9 63.5 76.9 -13.0
 SER-300   LEU-301  4.5 5.0 6.2 6.0 123.3 131.0 -46.1
 LEU-301   ASP-302  2.5 3.3 2.1 2.8 101.2 98.5 -12.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees