Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-639   ALA-640  9.3 8.4 -2.1 17.4 32.1 36.1 -16.2
 ALA-640   ASP-641  7.1 6.1 -23.5 -5.2 98.6 99.5 -0.8
 ASP-641   PHE-642  4.2 2.6 -27.2 3.6 98.6 121.7 -8.1
 PHE-642   GLY-643  1.8 3.0 -48.4 -37.7 72.5 62.2 66.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-662   PRO-663  8.9 10.9 -48.3 20.8 48.1 92.1 25.3
 PRO-663   VAL-664  6.9 7.6 -85.8 -19.7 22.3 48.2 111.8
 VAL-664   LYS-665  7.7 8.0 16.9 -12.2 136.8 137.0 2.9
 LYS-665   TRP-666  6.4 6.3 12.4 -2.7 85.3 77.1 -5.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees