Lysine-Specific Histone Demethylase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-420   LYS-421  4.7 4.8 -6.7 6.2 88.4 92.1 54.5
 LYS-421   HIS-422  5.0 5.4 0.7 -3.3 36.0 35.4 -12.9
 HIS-422   VAL-423  3.9 4.3 3.5 3.8 93.4 94.5 -2.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-506   LYS-507  23.2 23.1 20.1 -7.5 82.0 91.8 -45.2
 LYS-507   LEU-508  20.0 20.2 21.2 -26.2 24.8 26.7 -69.0
 LEU-508   GLN-509  20.0 19.8 30.0 -20.8 85.7 80.9 56.2
 GLN-509   GLU-510  20.5 20.4 11.8 -10.4 58.9 59.1 -34.0
 GLN-509   GLU-510  20.5 20.4 11.8 -10.4 58.9 59.1 -34.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-509   GLU-510  20.5 20.4 11.8 -10.4 58.9 59.1 -34.0
 GLN-509   GLU-510  20.5 20.4 11.8 -10.4 58.9 59.1 -34.0
 GLU-510   LEU-511  17.9 17.5 18.6 -37.5 123.4 121.5 177.8
 LEU-511   GLU-512  15.2 15.0 8.8 29.4 140.7 144.4 -319.9
 GLU-512   ALA-513  15.8 16.2 -58.4 42.9 101.3 102.5 66.7
 ALA-513   ASN-514  16.4 16.1 -2.2 12.5 63.2 70.7 -150.2
 ALA-513   ASN-514  16.4 16.1 -2.2 12.5 63.2 70.7 -150.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-513   ASN-514  16.4 16.1 -2.2 12.5 63.2 70.7 -150.2
 ALA-513   ASN-514  16.4 16.1 -2.2 12.5 63.2 70.7 -150.2
 ASN-514   PRO-515  12.9 12.5 11.0 -5.1 56.7 51.5 28.9
 PRO-515   PRO-516  10.6 10.2 2.6 -0.8 104.2 107.1 65.2
 PRO-516   SER-517  7.0 6.5 5.3 -11.5 41.9 47.3 -98.9
 SER-517   ASP-518  6.5 5.8 -1.8 5.8 154.3 164.8 98.9
 ASP-518   VAL-519  6.4 6.3 -8.3 6.6 112.1 116.4 13.3
 VAL-519   TYR-520  5.3 5.3 2.8 -7.5 136.9 137.1 24.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees