Hiv-1 Reverse Transcriptase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLN-242   PRO-243  12.6 12.0 15.7 15.4 104.2 104.4 -48.5
 PRO-243   ILE-244  10.4 10.5 -16.2 -9.1 33.8 52.9 70.6
 ILE-244   VAL-245  7.4 6.9 -25.5 30.8 66.0 77.0 -33.0
 VAL-245   LEU-246  7.5 7.6 -33.3 7.9 36.8 58.9 96.6
 LEU-246   PRO-247  5.5 5.2 -41.4 14.0 47.8 56.3 54.8
 PRO-247   GLU-248  7.1 6.8 24.9 -61.6 85.9 79.8 16.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-310   LYS-311  4.5 4.2 -38.4 39.9 76.6 71.0 -17.2
 LYS-311   GLU-312  8.0 7.9 3.9 -32.7 146.5 139.5 82.0
 GLU-312   PRO-313  7.0 7.5 27.7 2.5 81.1 89.2 -11.6
 PRO-313   VAL-314  7.9 7.6 27.4 -84.9 133.4 133.6 119.4
 VAL-314   HIS-315  7.1 6.8 -10.7 51.0 67.9 101.1 -23.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees