Importin Alpha Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 CYS-243   ARG-244  5.4 5.3 5.4 -11.1 106.0 104.8 10.5
 ARG-244   GLY-245  7.4 7.3 -2.2 13.4 133.5 134.5 94.4
 GLY-245   LYS-246  9.5 9.6 20.5 -39.6 58.3 57.7 -128.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LYS-247   PRO-248  12.0 13.0 159.3 -2.9 101.2 139.5 833.3
 PRO-248   GLN-249  11.3 11.3 -23.5 1.9 115.7 122.3 -70.3
 GLN-249   PRO-250  7.5 7.8 -0.1 1.0 62.1 65.6 25.4
 PRO-250   ASP-251  6.2 6.3 -20.3 14.8 44.7 48.0 67.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-259   PRO-260  7.9 7.6 -2.8 0.3 67.3 66.5 23.5
 PRO-260   THR-261  11.7 11.4 -7.5 5.1 42.9 41.9 31.2
 THR-261   LEU-262  11.8 11.8 -2.2 2.4 36.3 38.4 -12.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 LEU-265   ILE-266  11.3 11.2 4.9 1.0 39.5 40.6 55.2
 ILE-266   TYR-267  9.4 9.2 7.9 -15.4 52.1 48.8 -8.1
 TYR-267   SER-268  12.8 12.5 3.7 4.0 55.6 61.9 11.8
 SER-268   MET-269  12.9 12.9 -7.2 29.6 156.3 171.8 303.0
 MET-269   ASP-270  12.5 13.5 -22.5 -1.5 109.5 102.0 -179.4
 ASP-270   THR-271  12.2 12.5 1.6 -7.6 96.2 94.4 -32.9
 THR-271   GLU-272  8.9 9.1 4.5 -2.4 136.0 134.0 -0.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ILE-281   SER-282  1.9 1.6 -6.3 4.1 85.7 88.6 -1.4
 SER-282   TYR-283  2.3 2.5 1.0 3.6 36.3 37.5 52.4
 TYR-283   LEU-284  3.2 3.4 0.4 4.2 36.2 34.2 47.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees