72 Kda Type IV Collagenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-33   ILE-34  20.8 21.1 7.4 -58.1 76.5 56.3 -167.6
 ILE-34   ILE-35  18.4 18.7 -19.4 -1.6 52.8 75.2 16.5
 ILE-35   LYS-36  17.4 17.8 0.7 4.7 70.3 68.3 1.4
 LYS-36   PHE-37  16.6 16.3 8.3 10.8 128.5 140.6 -64.1
 PHE-37   PRO-38  13.2 13.3 5.5 -20.3 100.6 104.4 52.6
 PRO-38   GLY-39  13.3 13.9 -51.3 89.8 130.5 107.1 113.1
 GLY-39   ASP-40  14.0 12.5 -29.3 18.6 152.0 162.6 -42.2
 ASP-40   VAL-41  12.6 11.6 -20.8 14.2 133.7 133.9 -16.6
 VAL-41   ALA-42  14.3 12.3 -21.7 -3.6 98.5 122.8 1.0
 ALA-42   PRO-43  17.2 15.4 -10.1 0.2 147.5 168.2 -23.1
 PRO-43   LYS-44  16.4 15.0 -2.0 9.9 140.2 121.5 21.6
 LYS-44   THR-45  17.6 17.2 4.3 29.4 71.1 60.6 82.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-337   SER-338  7.7 7.7 -27.7 36.9 104.2 121.7 7.9
 SER-338   THR-339  5.9 5.5 -42.5 16.1 74.3 65.0 84.8
 THR-339   VAL-340  2.3 2.2 0.7 5.2 122.5 125.0 14.5
 VAL-340   GLY-341  3.1 3.0 -8.4 6.2 94.7 96.6 -29.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-344   GLU-345  5.3 5.6 11.6 62.0 68.7 80.8 148.2
 GLU-345   GLY-346  7.1 7.6 -53.9 -33.0 58.8 100.1 -58.2
 GLY-346   ALA-347  6.4 5.3 64.0 -20.6 106.7 138.8 -106.7
 ALA-347   PRO-348  3.7 3.7 -2.8 11.7 120.5 107.7 -7.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 CYS-390   PRO-391  3.2 3.1 11.9 5.8 33.0 28.6 52.3
 PRO-391   ASP-392  3.0 3.2 -7.1 15.5 131.6 130.9 52.2
 ASP-392   GLN-393  4.3 4.1 -10.9 5.7 122.6 126.6 1.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees