Isocitrate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-118   PRO-119  4.9 6.2 -14.5 17.1 77.6 75.1 -10.9
 PRO-119   ARG-120  5.1 5.7 -41.4 19.7 34.8 23.9 83.8
 ARG-120   LEU-121  5.8 6.2 15.6 7.5 72.3 87.2 7.9
 LEU-121   VAL-122  7.2 7.1 19.0 -40.2 115.8 101.5 43.9
 VAL-122   PRO-123  9.6 10.3 27.6 -18.7 82.1 75.0 39.6
 PRO-123   GLY-124  11.3 11.5 38.3 -23.6 137.9 126.0 -43.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-270   ASN-271  8.1 9.0 -50.1 -140.8 50.9 51.9 -279.5
 GLY-286   SER-287  1.4 1.6 169.0 103.9 95.1 88.5 -5.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees