Sodium-Dependent Serotonin Transporter

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-117   LEU-118  8.6 7.3 -7.2 3.5 83.4 85.1 5.1
 LEU-118   LEU-119  7.9 5.9 -6.7 -5.5 18.1 22.1 32.6
 LEU-119   PRO-120  8.8 7.0 7.4 4.0 119.0 126.8 -17.2
 PRO-120   TYR-121  6.0 5.1 -11.0 2.2 116.0 107.6 -4.6
 TYR-121   THR-122  3.6 2.0 2.2 -3.1 110.9 108.9 3.4
 THR-122   ILE-123  5.7 3.7 0.2 -11.3 169.1 172.1 26.8
 ILE-123   MET-124  5.0 3.7 13.9 -3.8 97.7 109.2 -16.6
 MET-124   ALA-125  1.4 0.3 -1.0 0.1 110.6 106.7 -6.6
 ALA-125   ILE-126  4.3 3.5 1.2 2.2 134.5 131.5 -5.6
 ILE-126   PHE-127  7.0 5.9 -3.2 6.7 29.0 20.4 -7.2
 PHE-127   GLY-128  4.8 4.1 -13.7 0.8 93.7 85.5 2.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees