Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-638   ILE-639  11.2 10.5 3.2 2.4 81.7 81.4 -4.4
 ILE-639   ALA-640  7.5 6.8 1.9 12.1 152.0 148.7 -17.2
 ALA-640   ASP-641  5.4 4.8 -18.3 -2.5 96.3 98.8 4.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-660   ARG-661  15.5 17.6 -164.0 -28.0 54.5 49.6 -222.6
 ARG-661   LEU-662  13.4 14.0 6.1 38.6 121.5 100.4 -16.0
 LEU-662   PRO-663  10.9 13.2 -40.0 13.7 52.5 82.0 26.2
 PRO-663   VAL-664  8.9 9.8 -82.5 -15.0 15.2 42.7 124.5
 VAL-664   LYS-665  10.2 10.7 13.4 -6.3 137.9 139.6 -2.9
 LYS-665   TRP-666  9.1 9.3 5.9 0.5 92.8 85.6 -4.2
 TRP-666   MET-667  5.4 5.7 4.1 8.1 95.5 91.7 3.2
 MET-667   ALA-668  6.4 6.8 -8.8 13.4 23.8 29.9 -4.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees