Syk Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PRO-115   LYS-116  13.7 14.0 -3.3 -0.6 102.1 99.8 12.0
 LYS-116   THR-117  11.7 12.1 17.0 -17.2 13.1 15.5 -4.1
 PRO-152   GLN-153  9.5 9.2 -9.9 -35.9 104.7 88.1 -62.5
 GLN-153   LEU-154  6.9 5.6 23.1 -8.3 106.5 101.6 -35.0
 LEU-154   GLU-155  8.6 7.2 19.6 -18.9 150.4 157.7 2.9
 GLU-155   LYS-156  7.7 6.8 13.7 2.7 86.4 95.5 6.1
 LYS-156   LEU-157  4.1 3.1 -10.8 -1.5 112.8 100.3 -24.1
 LEU-157   ILE-158  6.2 5.4 -6.0 21.2 50.5 49.6 -46.0

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Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees