Importin Alpha Subunit

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-200   ALA-201  17.1 17.5 -2.9 -2.4 114.8 113.1 -116.4
 ALA-201   GLY-202  14.3 14.6 19.2 -10.0 61.0 56.5 36.2
 GLY-202   ASP-203  16.8 17.3 -4.2 -7.1 55.3 57.3 222.9
 ASP-203   SER-204  18.7 19.0 -9.7 21.7 83.9 84.9 -153.0
 SER-204   THR-205  16.9 16.9 -7.8 5.4 91.5 98.1 -125.9
 THR-205   ASP-206  13.7 13.8 4.6 -5.9 149.2 145.6 28.9
 ASP-206   TYR-207  13.1 13.0 -8.3 8.4 93.1 92.6 99.9
 TYR-207   ARG-208  13.4 13.4 -4.1 3.7 135.3 139.1 -12.4
 ARG-208   ASP-209  11.4 11.6 0.3 -2.0 112.8 111.4 20.7
 ASP-209   TYR-210  8.4 8.5 2.7 -0.3 132.6 134.3 -63.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-238   LEU-239  14.6 15.0 1.8 1.4 85.3 85.9 -23.3
 LEU-239   SER-240  11.0 11.4 2.9 -0.5 74.1 74.7 30.9
 SER-240   ASN-241  12.1 12.3 0.1 -1.6 141.6 141.6 92.2
 ASN-241   LEU-242  13.5 13.6 -0.6 7.2 58.1 58.9 -140.9
 LEU-242   CYS-243  10.1 10.2 -7.6 7.8 114.2 114.2 -45.4
 CYS-243   ARG-244  8.7 8.7 -10.8 10.1 94.2 92.6 33.6
 ARG-244   GLY-245  12.1 12.1 -15.8 20.7 38.8 38.5 -78.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-261   LEU-262  8.8 8.8 -9.1 12.7 124.2 126.6 46.3
 LEU-262   ALA-263  7.2 7.4 -6.3 13.3 163.6 163.0 142.5
 ALA-263   LYS-264  5.8 6.1 -10.5 7.6 121.3 121.3 8.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-266   TYR-267  9.8 9.9 6.7 -9.6 151.9 152.5 41.7
 TYR-267   SER-268  11.4 11.7 6.5 -5.2 84.1 81.3 18.6
 SER-268   MET-269  14.8 15.0 0.2 2.3 133.4 131.7 -73.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-271   GLU-272  18.8 19.2 0.3 2.3 155.7 157.0 -31.0
 GLU-272   THR-273  19.4 19.7 -5.2 2.8 65.9 67.6 -34.8
 THR-273   LEU-274  16.6 16.8 -7.9 10.2 113.4 117.2 93.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-275   ASP-276  15.6 15.7 1.0 -3.6 28.0 30.1 -22.9
 ASP-276   ALA-277  14.7 14.6 9.3 -4.8 89.7 87.9 75.3
 ALA-277   CYS-278  11.2 11.2 7.0 -3.6 110.4 110.2 -42.0
 CYS-278   TRP-279  10.8 10.6 -7.2 6.8 131.6 131.8 41.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-280   ILE-281  9.9 9.7 0.5 2.3 109.2 107.3 -6.1
 ILE-281   SER-282  7.3 7.0 1.1 -2.8 93.8 91.3 88.2
 SER-282   TYR-283  10.1 9.8 3.1 -2.3 26.3 24.3 17.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-284   SER-285  6.7 6.6 15.2 -12.2 57.4 57.2 26.2
 SER-285   ASP-286  8.1 8.1 -8.9 13.5 75.2 74.9 -27.9
 ASP-286   GLY-287  11.5 11.6 18.3 -26.1 133.2 131.8 161.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees