Basic Fibroblast Growth Factor Receptor 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-481   LYS-482  5.7 5.4 -1.0 6.8 27.8 26.5 -66.0
 LYS-482   PRO-483  7.4 7.2 -18.9 5.9 35.5 30.5 88.8
 PRO-483   LEU-484  6.4 6.4 -10.7 17.1 79.1 68.5 -33.7

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-490   GLN-491  6.4 6.9 14.4 32.0 124.5 104.3 -80.4
 GLN-491   VAL-492  4.7 5.4 6.2 -3.2 140.3 139.7 27.4
 VAL-492   VAL-493  1.9 2.5 8.2 -0.4 135.5 134.8 -17.8
 VAL-493   LEU-494  2.8 3.0 16.1 -6.0 140.2 128.4 7.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-509   LYS-510  6.1 5.9 17.8 -10.9 44.8 42.0 -9.2
 LYS-510   VAL-511  4.6 4.6 -5.7 10.8 142.1 137.3 84.5
 VAL-511   ALA-512  4.3 4.3 -3.6 11.1 137.3 135.0 9.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees