DNA Mismatch Repair Protein Muts

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  VAL-114   THR-115  0.8 0.7 12.5 14.2 55.6 50.1 50.2  THR-115   PRO-116  2.9 3.1 -13.9 1.0 52.6 52.2 24.7  PRO-116   GLY-117  6.3 6.2 -5.4 14.9 69.0 67.2 -3.4 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees