Fatty Acid Synthase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 GLY-607   GLN-608  11.3 12.1 -4.2 0.5 165.5 165.0 -37.1
 GLN-608   CYS-609  12.0 12.9 3.9 -5.7 64.1 60.5 -3.6
 CYS-609   ILE-610  8.3 9.3 -10.4 16.5 73.6 74.4 12.6
 ILE-610   LYS-611  8.4 8.6 -16.8 10.3 124.8 124.4 -39.0
 LYS-611   GLU-612  11.7 11.9 -13.5 28.2 160.9 165.6 122.7
 GLU-612   ALA-613  9.9 10.8 -31.0 40.1 98.9 106.7 -31.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 ALA-641   CYS-642  5.0 4.6 2.0 3.6 53.6 50.6 83.0
 CYS-642   HIS-643  3.5 3.3 -4.9 5.3 158.7 158.6 -5.7
 HIS-643   ASN-644  2.7 2.4 2.7 -0.7 54.3 51.5 1.6
 ASN-644   SER-645  3.6 3.4 -1.6 -1.8 167.8 165.3 -27.9
 SER-645   LYS-646  3.2 3.0 1.2 0.4 76.8 80.9 -2.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees

Residue
i		 Residue
i+1		 Distance of hinge axis to residue i in conformer 1
(A) 		Distance of hinge axis to residue i in conformer 2
(A) 		Change in psi (i)
(deg) 		Change in phi (i+1)
(deg) 		Angle of psi(i) axis to hinge axis conformer 1
(deg) 		Angle of psi(i) axis to hinge axis conformer 2
(deg) 		Percentage Progress
 PHE-686   MET-687  6.6 6.4 14.0 -7.1 115.8 106.5 -44.2
 MET-687   GLU-688  3.2 3.1 -5.3 -6.8 50.7 52.3 71.7
 GLU-688   ALA-689  3.0 2.2 2.1 -0.5 161.3 161.7 3.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees