3-Isopropylmalate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-100   ALA-101  4.2 4.4 -9.2 16.7 44.1 46.7 -19.9
 ALA-101   ASN-102  2.1 1.5 -29.5 13.7 35.9 26.2 33.0
 ASN-102   LEU-103  2.5 2.5 2.9 -10.7 127.9 125.9 16.2
 LEU-103   ARG-104  0.6 0.6 -1.3 5.5 18.8 17.8 -0.5

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-109   PRO-110  9.1 7.4 -21.3 5.7 148.3 153.3 -62.5
 PRO-110   GLY-111  11.7 9.4 -155.0 177.6 144.8 148.8 77.6
 GLY-111   LEU-112  10.6 8.6 6.3 -14.1 88.9 84.9 17.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ARG-114   LEU-115  4.8 3.1 9.9 4.9 68.9 71.9 24.4
 LEU-115   SER-116  1.7 0.9 7.2 -2.7 57.4 59.1 -10.6
 SER-116   PRO-117  4.1 4.1 -9.8 -6.1 59.1 57.5 55.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLY-252   SER-253  1.5 2.3 -52.9 52.2 87.2 83.5 -49.0
 SER-253   LEU-254  3.7 2.8 -30.1 -7.6 16.7 20.2 162.0
 LEU-254   GLY-255  6.0 4.9 -0.5 2.2 71.0 71.0 -3.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-259   ALA-260  4.4 4.5 -14.5 17.3 147.7 148.6 5.7
 ALA-260   SER-261  4.9 5.0 -4.0 1.8 133.3 130.8 28.4
 SER-261   LEU-262  4.5 4.8 -10.9 1.3 144.8 149.0 -45.5
 LEU-262   GLY-263  3.7 4.2 -7.1 33.0 141.9 150.2 102.2
 GLY-263   ARG-264  3.4 4.3 -22.9 4.1 148.6 130.1 -64.1
 ARG-264   GLY-265  4.8 5.3 149.1 146.3 95.2 89.9 59.5
 GLY-265   THR-266  8.5 9.0 161.4 -63.2 137.6 129.6 -378.2
 THR-266   PRO-267  10.5 9.4 47.8 -106.5 146.8 149.5 250.4
 PRO-267   VAL-268  8.4 8.7 10.1 -24.5 140.9 131.5 25.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees