Pyruvate Kinase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 THR-113   LYS-114  8.1 8.3 -18.1 26.2 120.1 121.2 26.4
 LYS-114   GLY-115  6.2 6.9 -7.8 35.8 101.5 99.0 9.7
 GLY-115   PRO-116  2.5 3.2 -34.1 -4.4 101.5 84.6 8.8
 PRO-116   GLU-117  2.4 2.2 73.8 -45.0 42.0 40.5 95.4
 GLU-117   ILE-118  5.3 5.4 22.5 -7.7 99.2 93.7 -37.6
 ILE-118   ARG-119  8.6 8.7 -12.9 14.3 105.5 105.8 12.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ALA-213   ALA-214  11.1 11.1 2.1 16.1 44.2 39.9 85.4
 ALA-214   VAL-215  11.2 11.6 -31.3 26.5 141.8 144.9 -38.9
 VAL-215   ASP-216  8.9 9.1 -0.7 15.2 146.2 149.1 162.6
 ASP-216   LEU-217  9.7 10.2 -27.6 15.9 130.2 126.4 -142.4
 LEU-217   PRO-218  6.3 6.7 17.1 16.8 81.0 62.9 32.1
 PRO-218   ALA-219  4.6 5.1 -9.5 4.1 67.8 58.1 3.5
 ALA-219   VAL-220  3.4 5.2 31.1 -43.8 51.5 82.5 -19.0
 VAL-220   SER-221  2.8 2.7 51.9 -12.3 57.3 66.6 58.3
 SER-221   GLU-222  0.7 1.1 -9.8 2.7 138.4 145.5 -26.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees