Serine/threonine-Protein Kinase Pak 4

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-364   ASN-365  11.0 10.2 13.4 -12.6 92.4 64.2 -1.0
 ASN-365   GLU-366  8.7 7.3 9.2 -11.0 149.0 131.3 12.7
 GLU-366   VAL-367  8.1 5.8 15.4 -7.1 95.9 111.0 11.7
 VAL-367   VAL-368  7.0 6.0 21.9 -19.0 53.5 50.4 -8.2
 VAL-368   ILE-369  5.0 5.3 4.5 -3.9 101.0 88.5 -7.9
 ILE-369   MET-370  2.9 1.5 -0.2 -11.4 40.2 35.2 26.4
 MET-370   ARG-371  1.6 1.5 27.2 -25.6 81.4 106.8 8.5
 ARG-371   ASP-372  3.4 5.3 20.6 -11.0 58.4 70.1 -8.3
 ASP-372   TYR-373  2.2 6.3 11.2 -9.1 107.4 107.5 1.1
 TYR-373   GLN-374  3.3 5.4 24.3 -20.8 166.6 162.8 -23.0
 GLN-374   HIS-375  5.1 6.0 35.3 -15.2 97.3 103.3 2.7
 HIS-375   GLU-376  7.8 7.7 -5.1 -14.5 8.8 12.7 59.8
 GLU-376   ASN-377  9.4 8.5 8.5 7.6 113.0 107.7 -9.9
 ASN-377   VAL-378  9.2 8.7 -4.7 -9.9 109.7 105.2 -14.3
 VAL-378   VAL-379  5.9 5.6 26.2 -19.5 123.4 114.9 -20.4
 VAL-379   GLU-380  3.0 2.4 -19.6 1.0 121.2 139.8 -47.9
 GLU-380   MET-381  1.4 1.4 33.0 2.7 94.3 87.9 11.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 GLU-396   PHE-397  2.1 2.3 7.3 -38.8 125.4 131.4 71.4
 PHE-397   LEU-398  2.1 1.7 6.5 -14.9 104.8 123.6 17.9
 LEU-398   GLU-399  3.0 1.9 0.7 -2.9 150.2 143.1 51.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-455   LEU-456  8.2 7.6 5.5 -17.0 113.3 113.4 11.3
 LEU-456   SER-457  8.9 8.6 3.3 1.2 91.6 99.7 8.9
 SER-457   ASP-458  7.6 7.8 -6.3 1.1 57.2 56.7 11.5
 ASP-458   PHE-459  9.8 10.0 -27.4 -10.5 9.9 18.0 139.8
 PHE-459   GLY-460  8.8 9.2 -9.8 -104.8 62.7 51.7 132.3
 GLY-460   PHE-461  11.5 8.9 -162.7 40.6 45.1 124.1 -313.6
 PHE-461   CYS-462  13.5 10.4 -60.8 -9.5 44.2 133.5 -68.1
 CYS-462   ALA-463  10.8 7.7 -97.4 -46.2 19.6 123.1 361.6
 ALA-463   GLN-464  10.7 6.8 -134.5 51.9 66.4 117.9 -206.7
 GLN-464   VAL-465  8.4 10.1 61.1 46.7 154.9 13.1 -143.6
 VAL-465   SER-466  10.0 10.7 -71.5 34.9 60.6 114.6 -47.5
 LEU-475   VAL-476  22.2 23.6 -55.7 -32.9 142.2 98.8 -321.2
 VAL-476   GLY-477  19.6 26.9 -9.0 -39.3 127.5 109.6 -120.6
 GLY-477   THR-478  19.5 28.6 11.1 6.7 39.5 145.1 51.7
 THR-478   PRO-479  21.7 27.9 22.7 -48.3 97.8 97.7 148.8
 PRO-479   TYR-480  25.3 24.7 119.0 18.6 77.5 92.5 44.0
 TYR-480   TRP-481  25.9 25.9 13.0 -1.5 108.7 110.9 -2.2
 TRP-481   MET-482  23.0 22.9 -10.3 2.4 5.6 4.2 44.3
 MET-482   ALA-483  23.3 23.2 7.9 -6.6 119.7 118.2 -27.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees