Metabotropic Glutamate Receptor Subtype 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 SER-207   ASP-208  1.1 1.3 -13.5 13.4 105.5 107.8 2.7
 ASP-208   THR-209  2.8 2.6 -24.3 2.8 72.2 73.4 25.8
 THR-209   LEU-210  4.3 4.0 9.8 2.0 30.8 37.0 18.3
 LEU-210   GLN-211  4.9 4.7 23.1 -1.4 64.1 53.9 41.8

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-341   LEU-342  6.1 5.5 19.2 14.6 79.3 95.5 -21.7
 LEU-342   GLN-343  3.4 2.7 9.3 -11.2 151.9 162.8 14.2
 GLN-343   SER-344  1.9 1.8 11.8 7.2 91.9 85.9 14.9
 SER-344   PRO-345  5.4 5.4 -34.0 0.7 18.0 18.1 100.5
 PRO-345   GLU-346  6.5 6.1 -0.5 -2.1 81.8 86.1 15.7
 GLU-346   VAL-347  9.1 9.5 3.3 5.8 96.0 95.7 -27.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-472   GLY-473  9.7 10.2 -4.0 1.3 124.4 123.6 4.5
 GLY-473   ASP-474  10.7 11.0 2.3 2.4 44.2 46.8 2.5
 ASP-474   ALA-475  7.8 8.0 4.1 14.5 29.7 21.5 67.4
 ALA-475   PRO-476  8.3 7.9 1.6 5.8 61.7 68.1 -23.1
 PRO-476   GLY-477  7.4 7.6 3.6 57.4 53.7 66.8 102.2
 GLY-477   ARG-478  4.3 4.4 -43.1 24.9 108.1 159.7 -54.8
 ARG-478   TYR-479  2.8 3.6 -59.0 4.6 108.9 101.2 -24.5
 TYR-479   ASP-480  2.7 2.7 -9.8 24.8 153.1 150.7 28.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees