Striated-Muscle Alpha Tropomyosin

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  LEU-1185   SER-1186  7.0 8.5 11.3 -10.2 36.4 21.2 -45.0  SER-1186   GLU-1187  8.1 9.8 8.5 15.5 42.7 50.6 115.7  GLU-1187   GLY-1188  5.5 7.2 -25.5 16.7 67.8 88.2 -29.6  GLY-1188   LYS-1189  2.5 4.6 -18.2 7.7 95.8 103.4 -55.2  LYS-1189   CYS-1190  4.8 7.6 -20.8 25.2 156.9 167.2 -17.8  CYS-1190   ALA-1191  4.5 7.1 18.9 -25.6 82.5 76.5 70.1  ALA-1191   GLU-1192  1.6 3.9 -20.9 45.8 67.8 80.0 -62.2  GLU-1192   LEU-1193  4.7 6.4 -8.4 13.7 127.4 139.1 24.2  LEU-1193   GLU-1194  6.8 8.7 -3.8 12.7 150.6 144.6 49.3  GLU-1194   GLU-1195  5.5 6.3 -29.1 26.8 85.7 84.6 -40.2  GLU-1195   GLU-1196  7.3 7.4 -37.2 21.9 79.3 97.5 -19.8  GLU-1196   LEU-1197  10.0 10.7 35.3 -25.8 24.4 24.6 32.1 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees